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Recombinant NGFR 抗体 (AA 281-421)

This 兔 单克隆 antibody specifically detects NGFR in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN6654291
发货至: 中国
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Quick Overview for Recombinant NGFR 抗体 (AA 281-421) (ABIN6654291)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This NGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

NGFR-2550R
  • 抗原表位

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    AA 281-421

    原理

    Recombinant NGFR Antibody / p75NTR (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    A portion of amino acids 281-421 from the human protein was used as the immunogen for the recombinant NGFR antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant NGFR antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant NGFR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    NGFR

    背景

    This antibody is specific for a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or p75 Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR/p75NTR is a reliable marker for desmoplastic and neurotropic melanomas. It is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR/p75NTR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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