NGFR 抗体
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- 抗原 See all NGFR 抗体
- NGFR (Nerve Growth Factor Receptor (NGFR))
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适用
- 人, 兔, Cat, 雪貂, 猴, Baboon
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NGFR antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Differentiation (Diff), Staining Methods (StM)
- 特异性
- It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
- 无交叉反应
- 小鼠, 大鼠
- 纯化方法
- Purified by Protein A/G
- 免疫原
- NGFR from A875 melanoma cells
- 克隆位点
- NGFR5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product NGFR Primary Antibody
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 大鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibodyNGFR 适用: 人, 大鼠, 小鼠 WB, FACS, IF, IHC, ICC, IP, LCI 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, Non-Human Primate IHC, Diff, StM 宿主: 兔 Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 大鼠 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal MC192 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, Non-Human Primate, 兔, Cat, 雪貂 WB, FACS, IHC (p), ICC, IP, CyTOF 宿主: 小鼠 Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 小鼠 WB, IF, ELISA, IHC 宿主: 小鼠 Monoclonal 8G3G10 unconjugated
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- 应用备注
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Positive Control: Neuronal axons, Schwann cells and perineural cells of peripheral nerves or tumors of nerve sheath differentiation e. G. Schwannoma, Neurofibroma. Soma and axons of sensory neurons and ganglionic satellite cells. Melanomas.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- NGFR (Nerve Growth Factor Receptor (NGFR))
- 别名
- NGFR (NGFR 产品)
- 别名
- ngfr antibody, wu:fb38c02 antibody, wu:fc10h01 antibody, CD271 antibody, Gp80-LNGFR antibody, TNFRSF16 antibody, p75(NTR) antibody, p75NTR antibody, LNGFR antibody, RNNGFRR antibody, Tnfrsf16 antibody, p75 antibody, NRH1b antibody, fullback antibody, nrh1 antibody, p75ntr antibody, tnfrsf16 antibody, p75NGFR antibody, nerve growth factor receptor antibody, neurotrophin receptor associated death domain antibody, nerve growth factor receptor S homeolog antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, NGFR antibody, nradd antibody, Ngfr antibody, ngfr.S antibody
- 分子量
- 75kDa
- 基因ID
- 4804
- UniProt
- P08138
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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