CDK6 抗体 (AA 1-326)
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Quick Overview for CDK6 抗体 (AA 1-326) (ABIN6654089)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-326
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纯化方法
- Antigen affinity purified
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免疫原
- Human Cdk6 recombinant protein (amino acids M1-A326) was used as the immunogen for the Cdk6 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Cdk6 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Cdk6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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别名
- Cdk6
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背景
- Cell division protein kinase 6, also called Plstire, is an enzyme that in humans is encoded by the CDK6 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. Radiation hybrid analysis and inclusion within a mapped clone place the CDK6 gene at 7q21. Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation and promotes G1/S transition. This gene also involved in initiation and maintenance of cell cycle exit during cell differentiation. It prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types. In addition, CDK6 plays a role in promoting the proliferation of beta-cells in pancreatic islets of Langerhans.
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UniProt
- Q00534
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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