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CD40 Ligand 抗体

This 仓鼠 单克隆 antibody specifically detects CD40 Ligand in FACS 和 IHC (p). It exhibits reactivity toward 小鼠.
产品编号 ABIN6651981
发货至: 中国
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Quick Overview for CD40 Ligand 抗体 (ABIN6651981)

抗原

See all CD40 Ligand (CD40LG) 抗体
CD40 Ligand (CD40LG)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD40 Ligand antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MAB0712
  • 特异性

    This antibody detects Mouse CD40 Ligand. Other species not tested. Species: Mouse.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Mouse Th1 cells.

    亚型

    IgG2
  • 应用备注

    Flow Cytometry: 1/100-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/300.

    限制

    仅限研究用
  • 缓冲液

    PBS Stabilizers: None

    储存条件

    4 °C,-20 °C

    储存方法

    Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    cd154,cd40l

    背景

    CD40 ligand (CD40L), also known as CD154, TNFSF5, TRAP or gp39, is a 260 amino acid type II transmembrane glycoprotein belonging to the TNF family. Murine CD40L consists of a 22 aa cytoplasmic domain, a 24 aa transmembrane domain, and 214 aa extracellular domain bearing a single glycosylation site. CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, including NK cells, mast cells, basophils and eosinophils. Murine CD40L shares 78 % amino acid sequence identity with human CD40L. Native bioactive soluble CD40L exists. Soluble human trimeric CD40L secreted by stimulated T cells has been shown to be generated by proteolysis in the microsomes. Both membrane bound and soluble CD40L induce similar effects on B cells.

    UniProt

    P27548

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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