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PRKAA2 抗体

PRKAA2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 206CT5-4-2 unconjugated
产品编号 ABIN659096
发货至: 中国
  • 抗原 See all PRKAA2 抗体
    PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
    适用
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    宿主
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    小鼠
    克隆类型
    • 107
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    单克隆
    标记
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    This PRKAA2 antibody is un-conjugated
    应用范围
    • 107
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    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
    克隆位点
    206CT5-4-2
    亚型
    IgG2a kappa
    Top Product
    Discover our top product PRKAA2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
    别名
    PRKAA2 (PRKAA2 产品)
    背景
    The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
    分子量
    62320
    基因ID
    5563
    NCBI登录号
    NP_006243
    UniProt
    P54646
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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