This anti-Ret Proto-Oncogene antibody is a 小鼠 单克隆 antibody detecting Ret Proto-Oncogene in WB, IHC (p) 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze-thaw cycles.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
Wang, Zhang, Gao, Fan, Chen, Liu, Meng, Zhao, Ma: "Prognostic and Predictive Values of Subcellular Localisation of RET in Renal Clear-Cell Carcinoma." in: Disease markers, Vol. 2016, pp. 6870470, (2016) (PubMed).
抗原
Ret Proto-Oncogene (RET)
别名
RET
背景
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.