Neuregulin 3 抗体 (AA 311-360)
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北京 101111
Quick Overview for Neuregulin 3 抗体 (AA 311-360) (ABIN6579621)
抗原
See all Neuregulin 3 (NRG3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- Neuregulin-3 Antibody
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特异性
- Neuregulin-3 Polyclonal Antibody detects endogenous levels of Neuregulin-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360
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亚型
- IgG
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anti-Neuregulin 3 (NRG3) (Internal Region) antibody
NRG3 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 3 (NRG3) (AA 688-717) antibodyNRG3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2201 unconjugated
anti-Neuregulin 3 (NRG3) (AA 305-336) antibodyNRG3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1279-1280 unconjugated
anti-Neuregulin 3 (NRG3) (Internal Region) antibodyNRG3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 3 (NRG3) antibodyNRG3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 3 (NRG3) (AA 540-589) antibodyNRG3 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 3 (NRG3) antibodyNRG3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Neuregulin 3 (NRG3) antibodyNRG3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3810 unconjugated Recombinant Antibody
anti-Neuregulin 3 (NRG3) (AA 351-450) antibodyNRG3 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 3 (NRG3) (C-Term) antibodyVerified NRG3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Neuregulin 3 (NRG3)
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别名
- NRG3
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背景
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Synonyms: NRG3, Pro-neuregulin-3, membrane-bound isoform, Pro-NRG3
Background: This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis.This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcri
Gene Name: NRG3
Protein Name: Pro-neuregulin-3 membrane-bound isoform
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分子量
- '77 kDa
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基因ID
- 10718
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OMIM
- 605533
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UniProt
- P56975
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途径
- RTK signaling
抗原
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