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Neuregulin 3 抗体

NRG3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268859
发货至: 中国
  • 抗原 See all Neuregulin 3 (NRG3) 抗体
    Neuregulin 3 (NRG3)
    适用
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    宿主
    • 40
    • 1
    克隆类型
    • 40
    • 1
    单克隆
    标记
    • 15
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    • 2
    • 1
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    This Neuregulin 3 antibody is un-conjugated
    应用范围
    • 29
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    • 3
    • 1
    Western Blotting (WB)
    原理
    Neuregulin-3 (NRG3) Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Neuregulin-3 (Neuregulin-3 (NRG3))
    亚型
    IgG
    Top Product
    Discover our top product NRG3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Neuregulin 3 (NRG3)
    别名
    NRG3 (NRG3 产品)
    别名
    NRG3 antibody, HRG3 antibody, pro-NRG3 antibody, ska antibody, RGD1559678 antibody, neuregulin 3 antibody, pro-neuregulin-3, membrane-bound isoform antibody, NRG3 antibody, nrg3 antibody, LOC100478170 antibody, Nrg3 antibody
    背景
    This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009],HRG3, pro-NRG3,Cancer,ErbB-HER Signaling Pathway,Neuroscience,Signal Transduction,NRG3
    分子量
    56kDa
    基因ID
    10718
    UniProt
    P56975
    途径
    RTK signaling
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