SLAMF1 抗体 (AA 81-130)
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北京 101111
Quick Overview for SLAMF1 抗体 (AA 81-130) (ABIN6579561)
抗原
See all SLAMF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-130
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原理
- SLAM Antibody
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特异性
- SLAM Polyclonal Antibody detects endogenous levels of SLAM protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human SLAMF1. AA range:81-130
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亚型
- IgG
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anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 19-236) antibody
SLAMF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (Tyr1096) antibodySLAMF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 231-335) antibodySLAMF1 适用: 人 WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 69-204) antibodySLAMF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (FITC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 FITC
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibodySLAMF1 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal SLAM-4 unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 21-237) antibodySLAMF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (C-Term) antibodySLAMF1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (PE)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 PE
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (APC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 APC
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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别名
- SLAMF1
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背景
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Synonyms: SLAMF1, SLAM, Signaling lymphocytic activation molecule, CDw150, IPO-3, CD150
Background: domain:The most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues.,function:High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.,PTM:Phosphorylated by FYN.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subcellular location:Present on the surface of B-cells and T-cells.,subunit:Its cytoplasmic domain interacts with SH2 domain protein 1A (SH2D1A), and with PTPN11. Interacts with INPP5D/SHIP1. Binds to Measles virus HN protein and acts as a receptor for this virus.,tissue specificity:Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes, and a proportion of B-cells, and is rapidely induced on naive T-cells after activation.,
Gene Name: SLAMF1
Protein Name: Signaling lymphocytic activation molecule
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分子量
- 37 kDa
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基因ID
- 6504
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OMIM
- 603492
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UniProt
- Q13291
抗原
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