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SIGLEC8 抗体 (AA 81-130)

This 兔 多克隆 antibody specifically detects SIGLEC8 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6579554
发货至: 中国
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Quick Overview for SIGLEC8 抗体 (AA 81-130) (ABIN6579554)

抗原

See all SIGLEC8 抗体
SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

适用

人, 小鼠, 大鼠

宿主

  • 29
  • 11
  • 8
  • 1
兔

克隆类型

  • 31
  • 18
多克隆

标记

  • 32
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGLEC8 antibody is un-conjugated

应用范围

  • 28
  • 18
  • 14
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 81-130

    原理

    CD329 Antibody

    特异性

    CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC8. AA range:81-130

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

    别名

    SIGLEC8

    背景

    Synonyms: SIGLEC8, SAF2, Sialic acid-binding Ig-like lectin 8, Siglec-8, CDw329, Sialoadhesin family member 2, SAF-2, CD329

    Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],

    Gene Name: SIGLEC8

    Protein Name: Sialic acid-binding Ig-like lectin 8

    分子量

    54 kDa

    基因ID

    27181

    OMIM

    605639

    UniProt

    Q9NYZ4
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