SIGLEC8 抗体 (AA 81-130)
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北京 101111
Quick Overview for SIGLEC8 抗体 (AA 81-130) (ABIN6579554)
抗原
See all SIGLEC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-130
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原理
- CD329 Antibody
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特异性
- CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC8. AA range:81-130
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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别名
- SIGLEC8
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背景
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Synonyms: SIGLEC8, SAF2, Sialic acid-binding Ig-like lectin 8, Siglec-8, CDw329, Sialoadhesin family member 2, SAF-2, CD329
Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],
Gene Name: SIGLEC8
Protein Name: Sialic acid-binding Ig-like lectin 8
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分子量
- 54 kDa
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基因ID
- 27181
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OMIM
- 605639
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UniProt
- Q9NYZ4
抗原
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