JAG1 抗体 (AA 981-1030)
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北京 101111
Quick Overview for JAG1 抗体 (AA 981-1030) (ABIN6579536)
抗原
See all JAG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 981-1030
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原理
- Jagged1 Antibody
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特异性
- Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030
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亚型
- IgG
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应用备注
- IF 1:50-200 WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JAG1 (Jagged 1 (JAG1))
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别名
- JAG1
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背景
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Synonyms: JAG1, JAGL1, Protein jagged-1, Jagged1, hJ1, CD339
Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],
Gene Name: JAG1
Protein Name: Protein jagged-1
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分子量
- 133 kDa
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基因ID
- 182
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OMIM
- 601920
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UniProt
- P78504
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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