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CD42b 抗体 (AA 271-320)

This 兔 多克隆 antibody specifically detects CD42b in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN6579451
发货至: 中国
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Quick Overview for CD42b 抗体 (AA 271-320) (ABIN6579451)

抗原

See all CD42b (GP1BA) 抗体
CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

适用

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人

宿主

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兔

克隆类型

  • 51
  • 40
多克隆

标记

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This CD42b antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 271-320

    原理

    CD42b Antibody

    特异性

    CD42b Polyclonal Antibody detects endogenous levels of CD42b protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human GP1BA. AA range:271-320

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

    别名

    GP1BA

    背景

    Synonyms: GP1BA, Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b

    Background: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis.This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is

    Gene Name: GP1BA

    Protein Name: Platelet glycoprotein Ib alpha chain

    分子量

    71-145 kDa

    基因ID

    2811

    UniProt

    P07359
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