FMO3 抗体 (AA 101-150)
Our Local Distributor
北京 101111
Quick Overview for FMO3 抗体 (AA 101-150) (ABIN6579412)
抗原
See all FMO3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-150
-
原理
- FMO3 Antibody
-
特异性
- FMO3 Polyclonal Antibody detects endogenous levels of FMO3 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human FMO3. AA range:101-150
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
-
别名
- FMO3
-
背景
-
Synonyms: FMO3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase
Background: flavin containing monooxygenase 3(FMO3) Homo sapiens Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gen
Gene Name: FMO3
Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 3
-
分子量
- 60 kDa
-
基因ID
- 2328
-
UniProt
- P31513
抗原
-