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Dual Specificity Phosphatase 3 (DUSP3) (AA 136-185) 抗体

The 兔 多克隆 anti-Dual Specificity Phosphatase 3 antibody is suitable to detect Dual Specificity Phosphatase 3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN6579411
发货至: 中国
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (AA 136-185) 抗体 (ABIN6579411)

抗原

See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
Dual Specificity Phosphatase 3 (DUSP3)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 136-185

    原理

    VHR Antibody

    特异性

    VHR Polyclonal Antibody detects endogenous levels of VHR protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the C-terminal region of human DUSP3. AA range:136-185

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Dual Specificity Phosphatase 3 (DUSP3)

    别名

    DUSP3

    背景

    Synonyms: DUSP3, VHR, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, VHR

    Background: The protein encoded byThis gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast ca

    Gene Name: DUSP3

    Protein Name: Dual specificity protein phosphatase 3

    分子量

    20 kDa

    基因ID

    1845

    UniProt

    P51452

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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