IL-6 Receptor 抗体 (AA 221-270)
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北京 101111
Quick Overview for IL-6 Receptor 抗体 (AA 221-270) (ABIN6579241)
抗原
See all IL-6 Receptor (IL6R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-270
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原理
- IL-6Rα Antibody
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特异性
- IL-6Rα Polyclonal Antibody detects endogenous levels of IL-6Rα protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human IL6R. AA range:221-270
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亚型
- IgG
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anti-Interleukin 6 Receptor (IL6R) (AA 20-320) antibody
IL6R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 216-356) antibodyIL6R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (N-Term) antibodyIL6R 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 205-347) antibodyIL6R 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R 适用: 人 IHC, IP, ELISA, FACS, Func 宿主: 小鼠 Monoclonal B-R6 unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 385-462) antibodyIL6R 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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别名
- IL6R
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背景
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Synonyms: IL6R, Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126
Background: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011],
Gene Name: IL6R
Protein Name: Interleukin-6 receptor subunit alpha
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分子量
- 51 kDa
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基因ID
- 3570
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OMIM
- 147880
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UniProt
- P08887
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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