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p63 抗体 (C-Term)

This anti-p63 antibody is a 兔 多克隆 antibody detecting p63 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN657886
发货至: 中国

Quick Overview for p63 抗体 (C-Term) (ABIN657886)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

适用

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宿主

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克隆类型

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多克隆

标记

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This p63 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB30257
  • 抗原表位

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    AA 651-680, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TP63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from the C-terminal region of human TP63.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    TP63 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Zamudio, Wang, Chung, Wolosin: "Inhibition of TGF? cell signaling for limbal explant culture in serumless, defined xeno-free conditions." in: Experimental eye research, Vol. 145, pp. 48-57, (2015) (PubMed).

  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    TP63

    背景

    This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

    分子量

    76785

    基因ID

    8626

    NCBI登录号

    NP_001108450, NP_001108451, NP_001108452, NP_001108453, NP_001108454, NP_003713

    UniProt

    Q9H3D4
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