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MUC1 抗体 (C-Term)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN657546
发货至: 中国

Quick Overview for MUC1 抗体 (C-Term) (ABIN657546)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33144
  • 抗原表位

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    AA 1176-1205, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MUC1/EMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1176-1205 amino acids from the C-terminal region of human MUC1/EMA.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MUC1/EMA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Liu, Meng, Liu, Li, Wu, Zhang, E: "Hepatic epithelioid angiomyolipoma is a rare and potentially severe but treatable tumor: A report of three cases and review of the literature." in: Oncology letters, Vol. 11, Issue 6, pp. 3669-3675, (2016) (PubMed).

  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1/EMA

    背景

    This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

    分子量

    122102

    基因ID

    4582

    NCBI登录号

    NP_001018016, NP_001018017, NP_001037855, NP_001037856, NP_001037857, NP_001037858, NP_001191214, NP_001191215, NP_001191216, NP_001191217, NP_001191218, NP_001191219, NP_001191220, NP_00

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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