Anti-Replication Factor C p37 Mouse Monoclonal Antibody
特异性
This antibody recognizes the p37 subunit of human and yeast (S. cerevisiae) Replication Factor C (RFC). RFC is a heteropentameric protein consisting of p140, p40, p38, p37, and p36 subunits, RFC participates in targeting DNA polymerase delta processivity factor (PCNA) on to a primed DNA template during DNA synthesis and repair. RFC has also been associated with DNA repair in conjunction with a PCNA-like heterotrimer of Hus1, Rad1, and Rad9.
交叉反应
人, Saccharomyces cerevisiae
免疫原
Recombinant protein corresponding to the p37 subunit of human Replication Factor C expressed in E. coli.
Immunoblotting: use at 1:2,000 dilution. A band of 37 kD is detected. Positive controls: HeLa cell lysate.
限制
仅限研究用
状态
Liquid
溶解方式
Dilute in PBS or medium which is identical to that used in the assay system.
浓度
Lot specific
缓冲液
PBS, pH 7.4
储存条件
-80 °C
储存方法
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze-thaw cycles.
抗原
RFC4
(Replication Factor C (Activator 1) 4, 37kDa (RFC4))
别名
RFC4 / RFC37
背景
Replication factor C subunit 2,The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). {ECO:0000250}.,Nucleus,Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40