RFC4 抗体
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Quick Overview for RFC4 抗体 (ABIN190320)
抗原
See all RFC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Replication Factor C p37 Mouse Monoclonal Antibody
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特异性
- This antibody recognizes the p37 subunit of human and yeast (S. cerevisiae) Replication Factor C (RFC). RFC is a heteropentameric protein consisting of p140, p40, p38, p37, and p36 subunits, RFC participates in targeting DNA polymerase delta processivity factor (PCNA) on to a primed DNA template during DNA synthesis and repair. RFC has also been associated with DNA repair in conjunction with a PCNA-like heterotrimer of Hus1, Rad1, and Rad9.
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交叉反应
- 人, Saccharomyces cerevisiae
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免疫原
- Recombinant protein corresponding to the p37 subunit of human Replication Factor C expressed in E. coli.
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亚型
- IgG2b
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应用备注
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Immunoblotting: use at 1:2,000 dilution. A band of 37 kD is detected.
Positive controls: HeLa cell lysate. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium which is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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储存条件
- -80 °C
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储存方法
- This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze-thaw cycles.
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- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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别名
- RFC4 / RFC37
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背景
- Replication factor C subunit 2,The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). {ECO:0000250}.,Nucleus,Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40
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UniProt
- P35250
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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