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SOCS1 抗体

SOCS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5964161
发货至: 中国
  • 抗原 See all SOCS1 抗体
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    适用
    • 53
    • 37
    • 31
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    人, 小鼠, 大鼠
    宿主
    • 50
    • 5
    • 2
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 37
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS1 antibody is un-conjugated
    应用范围
    • 41
    • 20
    • 16
    • 10
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant Protein of human SOCS1
    亚型
    IgG
    Top Product
    Discover our top product SOCS1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    别名
    SOCS1 (SOCS1 产品)
    背景

    Synonyms: CISH 1,CISH1,Cytokine inducible SH2 protein 1,JAB,JAK binding protein,JAK-binding protein,Janus kinase binding protein,SOCS 1,SOCS-1,Socs1,SOCS1,SSI 1,SSI-1,SSI1,STAT induced STAT inhibitor 1,STAT-induced STAT inhibitor 1,Suppressor of cytokine signaling 1,Supressor of cytokine signalling 1,TEC interacting protein 3,Tec-interacting protein 3,TIP 3,TIP-3,TIP3

    Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

    分子量

    Observed_MW: 24kDa

    Calculated_MW: 23kDa

    基因ID
    8651
    UniProt
    O15524
    途径
    JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
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