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Diazepam Binding Inhibitor 抗体

This anti-Diazepam Binding Inhibitor antibody is a 兔 多克隆 antibody detecting Diazepam Binding Inhibitor in IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6567860
发货至: 中国

Quick Overview for Diazepam Binding Inhibitor 抗体 (ABIN6567860)

抗原

See all Diazepam Binding Inhibitor (DBI) 抗体
Diazepam Binding Inhibitor (DBI)

适用

  • 42
  • 16
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 46
  • 4

克隆类型

  • 47
  • 3
多克隆

标记

  • 28
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Diazepam Binding Inhibitor antibody is un-conjugated

应用范围

  • 38
  • 29
  • 15
  • 14
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human DBI (NP_001171513.1).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Diazepam Binding Inhibitor (DBI)

    别名

    DBI

    背景

    This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

    分子量

    Observed_MW: 11kDa

    Calculated_MW: 10kDa/11kDa/13kDa/14kDa/16kDa

    基因ID

    1622

    UniProt

    P07108
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