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Cyclin D3 抗体

The 兔 多克隆 anti-Cyclin D3 antibody is suitable to detect Cyclin D3 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN6566666
发货至: 中国
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Quick Overview for Cyclin D3 抗体 (ABIN6566666)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

适用

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人, 小鼠

宿主

  • 97
  • 15

克隆类型

  • 78
  • 34
多克隆

标记

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This Cyclin D3 antibody is un-conjugated

应用范围

  • 83
  • 34
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  • 15
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  • 9
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  • 1
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Western Blotting (WB)

质量等级

KO Validated
  • 特异性

    This antibody ist KO validated.

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human CCND3 (NP_001751.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cyclin D3 (CCND3)

    别名

    CCND3

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 36kDa

    Calculated_MW: 9kDa/22kDa/24kDa/32kDa

    基因ID

    896

    UniProt

    P30281

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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