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MUC1 抗体

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN6566576
发货至: 中国

Quick Overview for MUC1 抗体 (ABIN6566576)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human MUC1

    亚型

    IgG
  • 应用备注

    WB 1:1000 - 1:3000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    Synonyms: ADMCKD,ADMCKD1,Breast carcinoma associated antigen DF3,Breast carcinoma-associated antigen DF3,CA 15-3,CA15 3,CA15 3 antigen,CA15.3,Cancer antigen 15-3,Carcinoma associated mucin,Carcinoma-associated mucin,CD 227,CD227,DF3 antigen,EMA,Episialin,H23 antigen,H23AG,KL 6,KL-6,KL6,Krebs von den Lungen-6,MAM 6,MAM6,MCD,MCKD,MCKD1,Medullary cystic kidney disease 1 (autosomal dominant),Medullary cystic kidney disease,autosomal dominant,MUC 1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1,MUC1-alpha,MUC1-beta,MUC1-CT,MUC1-NT,MUC1/ZD,MUC1,Mucin 1,Mucin 1 transmembrane,Mucin 1,cell surface associated,Mucin-1 subunit beta,Peanut reactive urinary mucin,Peanut-reactive urinary mucin,PEM,PEMT,Polymorphic epithelial mucin,PUM,Tumor associated epithelial membrane antigen,Tumor associated epithelial mucin,Tumor associated mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin

    Background: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

    分子量

    Observed_MW: 122kDa

    Calculated_MW: 10-29kDa/103kDa/121-122kDa

    基因ID

    4582

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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