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CARD8 抗体

CARD8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5963070
发货至: 中国
  • 抗原 See all CARD8 抗体
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    适用
    人, 小鼠, 大鼠
    宿主
    • 35
    • 5
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD8 antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human CARD8
    亚型
    IgG
    Top Product
    Discover our top product CARD8 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    别名
    CARD8 (CARD8 产品)
    背景

    Synonyms: Apoptotic protein NDPP 1,Apoptotic protein NDPP1,CARD 8,CARD inhibitor of NF kappa B activating ligand,CARD inhibitor of NF kappaB activating ligand,CARD inhibitor of NF kappaB activating ligands,CARD-inhibitor of NF-kappa-B-activating ligand,CARD8,CARD8,CARDINAL,Caspase recruitment domain containing protein 8,Caspase recruitment domain family member 8,Caspase recruitment domain protein 8,Caspase recruitment domain-containing protein 8,DACAR,Dakar,DKFZp779L0366,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP 1,NDPP,NDPP1,TUCAN,Tumor up regulated CARD containing antagonist of CASP9,Tumor up regulated CARD containing antagonist of caspase 9,Tumor up-regulated CARD-containing antagonist of CASP9,tumor up-regulated CARD-containing antagonist of caspase nine,Tumor upregulated CARD containing antagonist of CASP9

    Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.

    分子量

    Observed_MW: 55kDa

    Calculated_MW: 32kDa/44kDa/48kDa/55kDa/60kDa

    基因ID
    22900
    UniProt
    Q9Y2G2
    途径
    Positive Regulation of Endopeptidase Activity
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