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- 抗原 See all GSAP (PION) 抗体
- GSAP (PION) (Pigeon Homolog (PION))
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抗原表位
- AA 537-565, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PION antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human PION.
- 克隆位点
- RB27384
- 亚型
- IgG
- Top Product
- Discover our top product PION Primary Antibody
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anti-Pigeon Homolog (PION) (AA 616-854) antibody
PION 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (AA 536-565), (C-Term) antibodyPION 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (N-Term) antibodyPION 适用: 人, 大鼠, 马, 兔, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- PION Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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- 抗原
- GSAP (PION) (Pigeon Homolog (PION))
- 别名
- PION (PION 产品)
- 别名
- PION antibody, A530088I07Rik antibody, Pion antibody, gamma-secretase activating protein antibody, GSAP antibody, Gsap antibody
- 背景
- Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD, MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1, MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP, MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).
- 分子量
- 97802
- 基因ID
- 54103
- NCBI登录号
- NP_059135
- UniProt
- A4D1B5
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