BTRC 抗体 (N-Term)
Quick Overview for BTRC 抗体 (N-Term) (ABIN655814)
抗原
See all BTRC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 17-52, N-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BTRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-52 amino acids from the N-terminal region of human BTRC.
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亚型
- Ig Fraction
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anti-beta-Transducin Repeat Containing (BTRC) (AA 24-151) antibody
BTRC 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4C5D8 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 50-340) antibodyBTRC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) antibodyBTRC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 397-448) antibodyBTRC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 1-605) antibodyBTRC 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (N-Term) antibodyBTRC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 52-354) antibodyBTRC 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) antibodyBTRC 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 701-1000) antibodyBTRC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 52-354) antibodyBTRC 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated
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应用备注
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- BTRC (beta-Transducin Repeat Containing (BTRC))
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别名
- BRTC1
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背景
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway.
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分子量
- 68867
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基因ID
- 8945
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NCBI登录号
- NP_003930, NP_378663
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UniProt
- Q9Y297
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途径
- Cell Division Cycle, Hedgehog Signaling
抗原
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