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Nibrin 抗体 (C-Term)

This anti-Nibrin antibody is a 兔 多克隆 antibody detecting Nibrin in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN655721
发货至: 中国

Quick Overview for Nibrin 抗体 (C-Term) (ABIN655721)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

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宿主

  • 111
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克隆类型

  • 98
  • 28
多克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB19072
  • 抗原表位

    • 39
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    AA 602-630, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Nibrin (NBN)

    别名

    NBN

    背景

    Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

    分子量

    84959

    基因ID

    4683

    NCBI登录号

    NP_002476

    UniProt

    O60934

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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