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CTLA4 抗体 (AA 50-78)

The 兔 多克隆 anti-CTLA4 antibody is suitable to detect CTLA4 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN654422
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CTLA4 抗体 (AA 50-78) (ABIN654422)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB23352
  • 抗原表位

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    AA 50-78

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This IDDM12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids of human IDDM12.

    亚型

    IgG
  • 应用备注

    WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    IDDM12

    背景

    CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    分子量

    24656

    基因ID

    1493

    NCBI登录号

    NP_001032720, NP_005205

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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