Angiopoietin 2 抗体 (C-Term)
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Quick Overview for Angiopoietin 2 抗体 (C-Term) (ABIN654062)
抗原
See all Angiopoietin 2 (ANGPT2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 404-432, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ANGPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human ANGPT2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 464-76, (2015) (PubMed).
: "Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models." in: Disease models & mechanisms, Vol. 7, Issue 3, pp. 387-96, (2014) (PubMed).
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: "Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 464-76, (2015) (PubMed).
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- Angiopoietin 2 (ANGPT2)
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别名
- ANGPT2
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背景
- The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
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分子量
- 56919
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基因ID
- 285
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NCBI登录号
- NP_001112359, NP_001112360, NP_001138
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UniProt
- O15123
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途径
- RTK signaling
抗原
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