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HDAC2 抗体 (AA 410-439)

Cited in 1 publication. This 兔 多克隆 anti-HDAC2 antibody (Clone RB24526) specifically detects HDAC2 in WB, IF, IHC (p) 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN653718
发货至: 中国
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Quick Overview for HDAC2 抗体 (AA 410-439) (ABIN653718)

抗原

See all HDAC2 抗体
HDAC2 (Histone Deacetylase 2 (HDAC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB24526
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    AA 410-439

    预测反应

    C, M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." in: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).

  • 抗原

    HDAC2 (Histone Deacetylase 2 (HDAC2))

    别名

    HDAC2

    背景

    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

    分子量

    55364

    基因ID

    3066

    NCBI登录号

    NP_001518

    UniProt

    Q92769

    途径

    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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