FLT1 抗体
Quick Overview for FLT1 抗体 (ABIN653260)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This VGFR1 antibody is generated from rabbits immunized with human VGFR1 recombinant protein.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "High VEGFR1/2 expression levels are predictors of poor survival in patients with cervical cancer." in: Medicine, Vol. 96, Issue 1, pp. e5772, (2017) (PubMed).
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: "High VEGFR1/2 expression levels are predictors of poor survival in patients with cervical cancer." in: Medicine, Vol. 96, Issue 1, pp. e5772, (2017) (PubMed).
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- VGFR1
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背景
- VGFR1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes.
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分子量
- 150769
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基因ID
- 2321
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NCBI登录号
- NP_001153392, NP_001153502, NP_001153503, NP_002010
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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