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HMGA1 抗体 (C-Term)

This anti-HMGA1 antibody is a 兔 多克隆 antibody detecting HMGA1 in WB, IF 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN653050
发货至: 中国

Quick Overview for HMGA1 抗体 (C-Term) (ABIN653050)

抗原

See all HMGA1 抗体
HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

适用

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宿主

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克隆类型

  • 64
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多克隆

标记

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This HMGA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB17645
  • 抗原表位

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    AA 64-93, C-Term

    预测反应

    Ha, M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This HMGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the C-terminal region of human HMGA1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Liu, Zhang, Li, Ding, Tu, Zhou, Qi, Chen, Sun: "Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1." in: International journal of oncology, Vol. 46, Issue 6, pp. 2526-34, (2015) (PubMed).

  • 抗原

    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

    别名

    HMGA1

    背景

    HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

    分子量

    11676

    基因ID

    3159

    NCBI登录号

    NP_002122, NP_665906, NP_665908, NP_665909, NP_665910, NP_665912

    UniProt

    P17096

    途径

    Nuclear Hormone Receptor Binding, Autophagy
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