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BMI1 抗体

This anti-BMI1 antibody is a 兔 多克隆 antibody detecting BMI1 in WB, IF, IHC (p) 和 FACS. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN652702
发货至: 中国

Quick Overview for BMI1 抗体 (ABIN652702)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

适用

  • 138
  • 54
  • 28
  • 10
  • 8
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  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 78
  • 58
  • 6

克隆类型

  • 78
  • 64
多克隆

标记

  • 86
  • 11
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BMI1 antibody is un-conjugated

应用范围

  • 108
  • 74
  • 44
  • 32
  • 29
  • 17
  • 12
  • 11
  • 4
  • 3
  • 3
  • 3
  • 2
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB22858
  • 纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BMI1 antibody is generated from rabbits immunized with BMI1 recombinant protein.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:2000. WB: 1:8000. IHC-P: 1:10~50. FC: 1:25. FC: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhou, Dai, Wu, Ji, Karaplis, Goltzman, Yang, Miao: "Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment." in: Scientific reports, Vol. 6, pp. 29171, (2018) (PubMed).

    León-González, Jara-Palacios, Abbas, Heredia, Schini-Kerth: "Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds." in: Food & function, Vol. 8, Issue 11, pp. 4062-4069, (2018) (PubMed).

    Dauleh, Santeramo, Fielding, Ward, Herrmann, Murray, Wilm: "Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158997, (2017) (PubMed).

  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    BMI1

    背景

    Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    分子量

    36949

    基因ID

    648

    NCBI登录号

    NP_001190991, NP_005171

    UniProt

    P35226

    途径

    Cell Division Cycle, Autophagy
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