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PSMA7 抗体 (AA 100-126)

This 兔 多克隆 anti-PSMA7 antibody (Clone RB21043) specifically detects PSMA7 in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN652603
发货至: 中国
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Quick Overview for PSMA7 抗体 (AA 100-126) (ABIN652603)

抗原

See all PSMA7 抗体
PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

适用

  • 54
  • 26
  • 18
  • 1
人, 小鼠

宿主

  • 46
  • 8

克隆类型

  • 46
  • 8
多克隆

标记

  • 26
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PSMA7 antibody is un-conjugated

应用范围

  • 44
  • 18
  • 16
  • 13
  • 8
  • 8
  • 6
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB21043
  • 抗原表位

    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-126

    预测反应

    X, B, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PSMA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-126 amino acids from the Central region of human PSMA7.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

    别名

    PSMA7

    背景

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA7 is a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension.

    分子量

    27887

    基因ID

    5688

    NCBI登录号

    NP_002783

    UniProt

    O14818

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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