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MICA 抗体 (AA 68-97)

Cited in 2+ publications. This anti-MICA antibody is a 兔 多克隆 antibody detecting MICA in WB, FACS, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN652566
发货至: 中国
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Quick Overview for MICA 抗体 (AA 68-97) (ABIN652566)

抗原

See all MICA 抗体
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

适用

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宿主

  • 44
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克隆类型

  • 64
  • 37
  • 2
多克隆

标记

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This MICA antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB21777
  • 抗原表位

    • 7
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    AA 68-97

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MICA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the Central region of human MICA.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. IF: 1:25. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Shi, Li, Couturier, Yang, Guo, He, Lewis, Zhou: "Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism." in: The open rheumatology journal, Vol. 9, pp. 60-4, (2015) (PubMed).

    Andresen, Skovbakke, Persson, Hagemann-Jensen, Hansen, Jensen, Skov: "2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 4, pp. 1847-55, (2012) (PubMed).

  • 抗原

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    别名

    MICA

    背景

    MICA is the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.

    分子量

    42915

    基因ID

    4276

    NCBI登录号

    NP_000238

    UniProt

    Q29983

    途径

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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