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LIM Domain Kinase 1 抗体 (pThr508)

The 兔 多克隆 anti-LIM Domain Kinase 1 antibody is suitable to detect LIM Domain Kinase 1 in samples from 人. It has been validated for DB.
产品编号 ABIN650882
发货至: 中国
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Quick Overview for LIM Domain Kinase 1 抗体 (pThr508) (ABIN650882)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体
LIM Domain Kinase 1 (LIMK1)

适用

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宿主

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克隆类型

  • 105
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多克隆

标记

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This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB28259
  • 抗原表位

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    pThr508

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LIMK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr508 of human LIMK1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    LIM Domain Kinase 1 (LIMK1)

    别名

    LIMK1

    背景

    There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. [provided by RefSeq].

    分子量

    72585

    基因ID

    3984

    NCBI登录号

    NP_001191355, NP_002305

    UniProt

    P53667

    途径

    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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