ADAM17 抗体 (Domain 17)
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北京 101111
Quick Overview for ADAM17 抗体 (Domain 17) (ABIN647517)
抗原
See all ADAM17 抗体适用
宿主
标记
应用范围
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抗原表位
- Domain 17
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特异性
- The ADAM17 goat antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.
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交叉反应
- 小鼠, 大鼠
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产品特性
- Goat Anti-ADAM17 / TACE, with HRP-conjugated secondary antibody
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免疫原
- Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3. was used as immunogen.
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亚型
- IgG
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anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) antibodyADAM17 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibodyADAM17 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB395 unconjugated Recombinant Antibody
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 201-300) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibodyADAM17 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyVerified ADAM17 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyKO Validated ADAM17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc) 宿主: 兔 Monoclonal 9E7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibodyADAM17 适用: 人 WB, ELISA, IHC, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (pThr735) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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溶解方式
- Supplied as 100 µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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别名
- ADAM17 / TACE
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背景
- ADAM17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), snake venom-like protease. Tumor necrosis factor beta (TNFbeta), also known as lymphotoxin, is a pleiotropic cytokine that has a molecular weight of 25 kDa. TNFalpha, also known as cachetin, is a 17 kDa cytokine that binds to the same receptors, producing an array of effects similar to those of TNFbeta. TNFbeta and TNFalpha share 30% amino acid homology and have similar biological activities. TNFbeta is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFalpha is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFbeta and TNFalpha can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFalpha converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFalpha precursor to release soluble TNFalpha.
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NCBI登录号
- NP_003174
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
抗原
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