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MUC1 抗体

The 小鼠 单克隆 anti-MUC1 antibody is suitable to detect MUC1 in samples from 人. It has been validated for FACS, IHC (p), IP 和 IHC (fro).
产品编号 ABIN643712
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUC1 抗体 (ABIN643712)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

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This MUC1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 原理

    Mouse Anti-Human Mucin 1

    特异性

    Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. DS-MB-01935 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. The dominant epitope recognized by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. DS-MB-01935 has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. This antibody also reacts weakly with sections of small intestine and colon.

    纯化方法

    Purified

    免疫原

    Human breast cancer cell line ZR-75-1.

    亚型

    IgG1
  • 应用备注

    Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin

    限制

    仅限研究用
  • 浓度

    IgG concentration 1.0 mg/ml

    缓冲液

    Phosphate buffered saline

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CD227

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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