MUC1 抗体
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北京 101111
Quick Overview for MUC1 抗体 (ABIN643712)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse Anti-Human Mucin 1
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特异性
- Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. DS-MB-01935 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. The dominant epitope recognized by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. DS-MB-01935 has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. This antibody also reacts weakly with sections of small intestine and colon.
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纯化方法
- Purified
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免疫原
- Human breast cancer cell line ZR-75-1.
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亚型
- IgG1
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应用备注
- Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- MUC1 (Mucin 1 (MUC1))
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别名
- CD227
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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