GAPDH 抗体 (C-Term)
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北京 101111
Quick Overview for GAPDH 抗体 (C-Term) (ABIN640717)
抗原
See all GAPDH 抗体适用
宿主
标记
应用范围
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抗原表位
- C-Term
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特异性
- DS-PB-00846 recognizes an epitope within the C-terminal (CT) region of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin. ImmunohistologyThis product requires antigen retrieval using heat treatment prior to staining of paraffin sections. TRIS/EDTA buffer pH9.0 is recommended for this purpose.
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交叉反应
- 犬
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产品特性
- Goat Anti-Human GAPDH (C-terminus)
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纯化方法
- Purified
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免疫原
- Peptide sequence C-HQVVSSDFNSDT corresponding to the C-terminal region of GAPDH (NP_002037.2).
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亚型
- IgG
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限制
- 仅限研究用
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浓度
- IgG concentration 0.5 mg/ml
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缓冲液
- TRIS buffered saline pH7.3
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
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别名
- GAPDH
抗原
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