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S100A8 抗体 (AA 30-110)

This anti-S100A8 antibody is a 兔 多克隆 antibody detecting S100A8 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6390101
发货至: 中国

Quick Overview for S100A8 抗体 (AA 30-110) (ABIN6390101)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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人, 小鼠, 大鼠

宿主

  • 118
  • 53
  • 3
  • 3
  • 3

克隆类型

  • 120
  • 60
多克隆

标记

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  • 1
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This S100A8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    • 1
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    AA 30-110

    原理

    Unconjugated Rabbit polyclonal to S10A8

    特异性

    S10A8 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    S10A8 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human S10A8 protein.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    说明

    Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S10A8

    分子量

    10 kDa

    基因ID

    6279

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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