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GDNF 抗体

GDNF 适用: 人 WB, ELISA, Inhibition 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN636726
发货至: 中国
  • 抗原 See all GDNF 抗体
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    适用
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    宿主
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    克隆类型
    • 72
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    多克隆
    标记
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    This GDNF antibody is un-conjugated
    应用范围
    • 76
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Purified
    免疫原
    GDNF antibody was raised in rabbit using highly pure recombinant human GDNF as the immunogen.
    Top Product
    Discover our top product GDNF Primary Antibody
  • 应用备注
    Optimal conditions should be determined byt he investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    别名
    GDNF (GDNF 产品)
    别名
    gdnf antibody, GDNF antibody, AI385739 antibody, gdnfa antibody, hfb1-gdnf antibody, ATF1 antibody, ATF2 antibody, HFB1-GDNF antibody, HSCR3 antibody, glial cell derived neurotrophic factor antibody, glial cell derived neurotrophic factor a antibody, glial cell line derived neurotrophic factor antibody, glial cell derived neurotrophic factor L homeolog antibody, Gdnf antibody, gdnfa antibody, GDNF antibody, gdnf.L antibody
    背景
    GDNF is a disulfide-linked homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFR a(a1-a4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability.
    途径
    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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