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RANKL 抗体

TNFSF11 适用: 小鼠 WB, ELISA, Inhibition 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN636714
发货至: 中国
  • 抗原 See all RANKL (TNFSF11) 抗体
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    适用
    • 167
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    小鼠
    宿主
    • 156
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    克隆类型
    • 171
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    多克隆
    标记
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    This RANKL antibody is un-conjugated
    应用范围
    • 170
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Purified
    免疫原
    RANKL antibody was raised in rabbit using highly pure recombinant murine sRANKL as the immunogen.
    Top Product
    Discover our top product TNFSF11 Primary Antibody
  • 应用备注
    ELISA: 0.5-2 µg/mL, Inhibition: 0.05 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    别名
    RANKL (TNFSF11 产品)
    别名
    CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, TNFSF11 antibody, Ly109l antibody, OPG antibody, Trance antibody, cd254 antibody, odf antibody, opgl antibody, optb2 antibody, rankl antibody, sodf antibody, tnfsf11 antibody, trance antibody, TNF superfamily member 11 antibody, tumor necrosis factor (ligand) superfamily, member 11 antibody, TNF receptor superfamily member 11b antibody, TNF superfamily member 11 L homeolog antibody, TNFSF11 antibody, Tnfsf11 antibody, TNFRSF11B antibody, tnfsf11.L antibody
    背景
    RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG.
    分子量
    19.4 kDa (predicted detection band MW)
    途径
    NF-kappaB Signaling
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