RANKL 抗体
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北京 101111
Quick Overview for RANKL 抗体 (ABIN636714)
抗原
See all RANKL (TNFSF11) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- RANKL antibody was raised in rabbit using highly pure recombinant murine sRANKL as the immunogen.
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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别名
- RANKL
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背景
- RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG.
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分子量
- 19.4 kDa (predicted detection band MW)
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途径
- NF-kappaB Signaling
抗原
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