PAI1 抗体
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- 抗原 See all PAI1 (SERPINE1) 抗体
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
- 纯化方法
- Purified
- 免疫原
- PAI1 antibody was raised in rabbit using highly pure recombinant human PAI-1 as the immunogen.
- Top Product
- Discover our top product SERPINE1 Primary Antibody
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anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibody
SERPINE1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (Internal Region) antibodyVerified SERPINE1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 86-185) antibodySERPINE1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D5 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人, 猴 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 6F3 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 141-389) antibodySERPINE1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-398) antibodySERPINE1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: >15 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from PBS, pH 7.2.
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- 抗原
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- 别名
- PAI1 (SERPINE1 产品)
- 别名
- PAI antibody, PAI-1 antibody, PAI1 antibody, PLANH1 antibody, SERPINE1 antibody, si:ch211-138a11.1 antibody, Planh1 antibody, PAI1A antibody, Pai1 antibody, Pai1aa antibody, Planh antibody, RATPAI1A antibody, serpin family E member 1 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 1 antibody, SERPINE1 antibody, serpine1.L antibody, serpine1 antibody, Serpine1 antibody
- 背景
- Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases.
- 分子量
- 42.7 kDa (predicted detection band MW)
- 途径
- p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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