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FASL 抗体

FASL 适用: 人 WB, ELISA, Inhibition 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN636623
发货至: 中国
  • 抗原 See all FASL 抗体
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    适用
    • 97
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    宿主
    • 68
    • 28
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    山羊
    克隆类型
    • 75
    • 41
    多克隆
    标记
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    This FASL antibody is un-conjugated
    应用范围
    • 78
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Purified
    免疫原
    FasL antibody was raised in goat using highly pure recombinant human FasL/Apo1 L as the immunogen.
    Top Product
    Discover our top product FASL Primary Antibody
  • 应用备注
    ELISA: 0.5-2 µg/mL, Inhibition: 0.08-0.1 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    别名
    FasL (FASL 产品)
    别名
    ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
    背景
    Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.
    分子量
    17.6 kDa (predicted detection band MW)
    途径
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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