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CD40 Ligand 抗体

CD40LG 适用: 人 WB, ELISA, Inhibition 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN636590
发货至: 中国
  • 抗原 See all CD40 Ligand (CD40LG) 抗体
    CD40 Ligand (CD40LG)
    适用
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    宿主
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    山羊
    克隆类型
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    多克隆
    标记
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    This CD40 Ligand antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Purified
    免疫原
    CD40 L antibody was raised in goat using highly pure recombinant human sCD40 as the immunogen.
    Top Product
    Discover our top product CD40LG Primary Antibody
  • 应用备注
    Optimal conditions should be determined byt he investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    CD40 Ligand (CD40LG)
    别名
    CD40L (CD40LG 产品)
    别名
    CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
    背景
    CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.
    分子量
    16.3 kDa (predicted detection band MW)
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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