MUC1 抗体 (N-Term)
Quick Overview for MUC1 抗体 (N-Term) (ABIN635866)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MUC1 antibody was raised against the N terminal of MUC1
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纯化方法
- Affinity purified
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免疫原
- MUC1 antibody was raised using the N terminal of MUC1 corresponding to a region with amino acids SATQRSSVPSSTEKNALSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQEL
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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MUC1 Blocking Peptide, (ABIN5614880), is also available for use as a blocking control in assays to test for specificity of this MUC1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MUC1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MUC1 (Mucin 1 (MUC1))
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别名
- MUC1
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背景
- MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
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分子量
- 27 kDa (MW of target protein)
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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