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Sonic Hedgehog 抗体

This anti-Sonic Hedgehog antibody is a 兔 多克隆 antibody detecting Sonic Hedgehog in WB 和 IHC. Suitable for 人, 小鼠, 斑马鱼 和 犬.
产品编号 ABIN635696
发货至: 中国

Quick Overview for Sonic Hedgehog 抗体 (ABIN635696)

抗原

See all Sonic Hedgehog (SHH) 抗体
Sonic Hedgehog (SHH)

适用

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人, 小鼠, 斑马鱼, 犬

宿主

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克隆类型

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多克隆

标记

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This Sonic Hedgehog antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purified

    免疫原

    Sonic Hedgehog antibody was raised using a synthetic peptide corresponding to a region with amino acids RCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKT
  • 应用备注

    WB: 1 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Sonic Hedgehog Blocking Peptide, catalog no. 33R-7837, is also available for use as a blocking control in assays to test for specificity of this Sonic Hedgehog antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SHH antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    Sonic Hedgehog (SHH)

    别名

    Sonic Hedgehog

    背景

    SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.

    分子量

    28 kDa (MW of target protein)

    途径

    Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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