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MUC1 抗体 (C-Term)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in IHC 和 WB. Suitable for 人, 小鼠 和 犬.
产品编号 ABIN635541
发货至: 中国

Quick Overview for MUC1 抗体 (C-Term) (ABIN635541)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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人, 小鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    MUC1 antibody was raised against the C terminal of MUC1

    纯化方法

    Affinity purified

    免疫原

    MUC1 antibody was raised using the C terminal of MUC1 corresponding to a region with amino acids GQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGNGGSSL
  • 应用备注

    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    MUC1 Blocking Peptide, (ABIN938886), is also available for use as a blocking control in assays to test for specificity of this MUC1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MUC1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

    分子量

    22 kDa (MW of target protein)

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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