PARL 抗体 (N-Term)
Quick Overview for PARL 抗体 (N-Term) (ABIN634971)
抗原
See all PARL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- PARL antibody was raised against the N terminal of PARL
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纯化方法
- Affinity purified
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免疫原
- PARL antibody was raised using the N terminal of PARL corresponding to a region with amino acids SLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQ
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应用备注
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WB: 0.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PARL Blocking Peptide, (ABIN5615220), is also available for use as a blocking control in assays to test for specificity of this PARL antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PARL antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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别名
- PARL
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背景
- PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.
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分子量
- 36 kDa (MW of target protein)
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途径
- Autophagy
抗原
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