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PARL 抗体 (N-Term)

This 兔 多克隆 anti-PARL antibody specifically detects PARL in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠 和 犬 samples.
产品编号 ABIN634971
发货至: 中国
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Quick Overview for PARL 抗体 (N-Term) (ABIN634971)

抗原

See all PARL 抗体
PARL (Presenilin Associated, Rhomboid-Like (PARL))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 18
  • 4
  • 2

克隆类型

  • 20
  • 4
多克隆

标记

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This PARL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    特异性

    PARL antibody was raised against the N terminal of PARL

    纯化方法

    Affinity purified

    免疫原

    PARL antibody was raised using the N terminal of PARL corresponding to a region with amino acids SLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQ
  • 应用备注

    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    PARL Blocking Peptide, (ABIN5615220), is also available for use as a blocking control in assays to test for specificity of this PARL antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PARL antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    PARL (Presenilin Associated, Rhomboid-Like (PARL))

    别名

    PARL

    背景

    PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.

    分子量

    36 kDa (MW of target protein)

    途径

    Autophagy
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