ULBP1 抗体 (N-Term)
Quick Overview for ULBP1 抗体 (N-Term) (ABIN634554)
抗原
See all ULBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ULBP1 antibody was raised against the N terminal of ULBP1
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纯化方法
- Affinity purified
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免疫原
- ULBP1 antibody was raised using the N terminal of ULBP1 corresponding to a region with amino acids MAAAASPAFLLCLPLLHLLSGWSRAGWVDTHCLCYDFIITPKSRPEPQWC
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anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibody
ULBP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A6F11 unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibodyULBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibodyULBP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-244) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-234) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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ULBP1 Blocking Peptide, (ABIN5616905), is also available for use as a blocking control in assays to test for specificity of this ULBP1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ULBP1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ULBP1 (UL16 Binding Protein 1 (ULBP1))
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别名
- ULBP1
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背景
- ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
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分子量
- 28 kDa (MW of target protein)
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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